A Rare Case of Granular Cell Tumor in the Right Upper Lung of an Adolescent Patient
Granular cell tumors (GCTs) are rare neoplasms of neuroectodermal origin characterized by large polygonal cells with abundant eosinophilic and granular cytoplasm. GCTs rarely affect the lungs, with only a few cases reported in the literature. The pathophysiology of this Schwann cell-derived condition is not well understood but is thought to be due to recurring genetic mutations. GCTs have been linked with Noonan syndrome. Here, we report the case of a 17-year-old caucasian male who presented with partial upper airway obstruction due to a GCT. This case promotes awareness among pathologists and clinicians for this condition in the workup of patients presenting with upper airway obstruction.
Grove, John; Meier, Casey; Youssef, Bahaaeldin; and Costello, Patrick, "A Rare Case of Granular Cell Tumor in the Right Upper Lung of an Adolescent Patient" (2022). ETSU Faculty Works. 265.