MS (Master of Science)
Date of Award
Committee Chair or Co-Chairs
Gregory W Bishop
Dane Scott William, Catherine McCusker, Hua Mei
Screen-printed carbon electrodes (SPCEs) have garnered much attention as sensors due to their simplicity and relatively low cost. However, to impart necessary selectivity and sensitivity for specific applications, modification of the SPCE surface, which can involve time-consuming procedures or costly equipment/materials, is typically required. Here, a simple nitrogen-doping process based on NH4OH was used to modify SPCEs prepared from commercially available ink for electrochemical detection of H2O2, a common target for biosensing strategies and indicator of cell stress. XPS studies showed that NH4OH treatment of SPCEs led to a nearly 5-fold increase in surface nitrogen content (from 0.28% to 1.34%). Compared to SPCEs, nitrogen-doped SPCEs (N-SPCEs) demonstrated enhanced current and lower onset potentials for H2O2 reduction. Amperometric detection of H2O2 at an applied potential of -0.4 V (vs. Ag/AgCl) using N-SPCEs also exhibited a wider linear range, lower detection limit, and higher sensitivity than SPCEs.
Thesis - embargo
Nkyaagye, Emmanuel, "Facile Nitrogen-Doping of Screen-Printed Carbon Electrodes for Detection of Hydrogen Peroxide" (2021). Electronic Theses and Dissertations. Paper 4007. https://dc.etsu.edu/etd/4007
Copyright by the authors.