Degree Name
MS (Master of Science)
Program
Chemistry
Date of Award
12-2026
Committee Chair or Co-Chairs
Abbas Shilabin
Committee Members
Sandy Eagle, Krishna Sharma
Abstract
As a leading cause of death worldwide, cancer and its treatments remain a primary source of interest among researchers. Modern studies are looking into bioselective cytotoxicity to create new chemotherapies that do not have the same harsh side effects as those we use today. Natural product research has a promising future for the development of such treatments. Specifically, polar flavonoids may be the key to a bioselective treatment. Such flavonoid species are native to plants, often within flower petals or within the body. A natural antioxidant, they are designed not to harm healthy cells. This study focuses on the plant species Chromolaena leivensis, native to Bogota, Columbia. As a lesser-known species with low levels of phytochemical exploration, there is a high likelihood of isolating a brand-new flavonoid. The results of the study proved the isolation and purification of cytotoxic flavonoid species.
Document Type
Thesis - unrestricted
Recommended Citation
Bryant, Luke A., "Phytochemical and In-Vitro Cytotoxic Analyses of Flavonid Species Isolated from Chromolaena leivensis" (2026). Electronic Theses and Dissertations. Paper 4770. https://dc.etsu.edu/etd/4770
Copyright
Copyright by the authors.
Included in
Chemical and Pharmacologic Phenomena Commons, Medical Biochemistry Commons, Medical Cell Biology Commons, Medicinal and Pharmaceutical Chemistry Commons, Natural Products Chemistry and Pharmacognosy Commons, Oncology Commons, Organic Chemicals Commons, Other Chemicals and Drugs Commons, Plants Commons, Polycyclic Compounds Commons
