Degree Name

MS (Master of Science)

Program

Chemistry

Date of Award

8-2009

Committee Chair or Co-Chairs

David G. J. Young

Committee Members

Jeffrey G. Wardeska, Yu-Lin Jiang

Abstract

Allenes are very important chemical reagents in organic synthesis. Due to their high reactivity, they have been extensively used to carry out a variety of unique and effective chemical transformations including but not limited to ionic and free radical additions and transition metal catalyzed cyclizations. As the chemistry of this group of compounds is explored further and their applications expanded there is a need to develop alternative and cost effective methods for their synthesis. Our approach involves the synthesis of allenes from oxa-bicyclo-alkan-2-ones by methyllithium induced Eschenmoser fragmentation of the bicyclotosylhydrazone derivatives.

Document Type

Thesis - Open Access

Copyright

Copyright by the authors.

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