Variability of FEV and Criterion for Acute Pulmonary Exacerbation
Excerpt: Morgan et al. (1) concluded that cystic fibrosis (CF) in children and adolescents with a high baseline forced expiratory volume (FEV1) were less likely to have a therapeutic intervention or slower rate of FEV1 decline after a single acute decline in FEV1 of 10%. This conclusion is not well supported due to the arbitrary criteria used for defining a pulmonary exacerbation, as explained below.
Jenkins, Bradlee A.; and Glenn, L. Lee. 2014. Variability of FEV and Criterion for Acute Pulmonary Exacerbation. Frontiers in Pediatrics. Vol.2(1). 114. https://doi.org/10.3389/fped.2014.00114 ISSN: 2296-2360