bHenoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be considered a form of immune complex-mediated leukocytoclastic vasculitis (LCV) involving the skin and other organs. Though it primarily affects children (over 90% of cases), the occurrence in adults has been rarely reported. Management often involves the use of immunomodulatory or immune-suppressive regimens.
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Jithpratuck, Warit; Elshenawy, Yasmin; Saleh, Hana; Youngberg, George; Chi, David S.; and Krishnaswamy, Guha. 2011. The Clinical Implications of Adult-Onset Henoch-Schonelin purpura. Clinical and Molecular Allergy. Vol.9 https://doi.org/10.1186/1476-7961-9-9