Metal-Catalyzed Intramolecular Hydrolysis of Phosphate Esters
A tridentate water-soluble phosphotriester ligand has been synthesized. Kinetics studies have shown that divalent metal ions dramatically enhance the rate of hydrolysis of such phosphotriester at 25 °C and pH 8.0 via intramolecular nucleophilic attack by a metal bound hydroxide.
Kady, Ismail O.; and Tan, Biao. 1995. Metal-Catalyzed Intramolecular Hydrolysis of Phosphate Esters. Tetrahedron Letters. Vol.36(23). 4031-4034. https://doi.org/10.1016/0040-4039(95)00709-L ISSN: 0040-4039