Update on Continuous Estrogen-Progestin Replacement Therapy
Estrogen replacement therapy is recommended for the prevention of osteoporosis and the attenuation of symptoms associated with menopause. Compliance may be a problem with sequential regimens of estrogen and progestin. To address this issue, continuous-dosing regimens of estrogen and progestin have been used. These regimens cause significantly less cyclic and intermenstrual bleeding and induce amenorrhea in most women, which should enhance compliance.
Rosenfeld, J. A.. 1994. Update on Continuous Estrogen-Progestin Replacement Therapy. American Family Physician. Vol.50(7). 1519-1523. https://pubmed.ncbi.nlm.nih.gov/7976988/ PMID: 7976988 ISSN: 0002-838X