Degree Name
MS (Master of Science)
Program
Biology
Date of Award
12-2022
Committee Chair or Co-Chairs
Justin Gass
Committee Members
Russell Brown, Leonard J. Robertson
Abstract
Alcohol use disorder (AUD) costs the U.S. billions of dollars each year and is a leading cause of preventable death. AUD leads to many health complications, and those who suffer from AUD will often have stress and anxiety disorder comorbidities. To better understand this connection between AUD and stress and anxiety disorders, restraint stress (RS) and chronic-intermittent ethanol exposure (CIE) procedures were used on rats to analyze neuroinflammation via ELISA in the infralimbic and prelimbic cortices, and the bed nucleus of the stria terminalis (BNST). Levels of proinflammatory cytokines, TNF-α and IL-1β, were found to be elevated across different tests in both males and females. This study builds upon previous work in the BNST and offers new information for future studies of stress and alcohol in the region.
Document Type
Thesis - unrestricted
Recommended Citation
Burski, Nicholas, "Alcohol, Stress, and Sex in the Bed Nucleus of the Stria Terminalis" (2022). Electronic Theses and Dissertations. Paper 4133. https://dc.etsu.edu/etd/4133
Copyright
Copyright by the authors.