MSEH (Master of Science in Environmental Health)
Date of Award
Committee Chair or Co-Chairs
Kurt Maier, Philip Scheuerman, Thabet Tolaymat
Silver nanoparticles (AgNPs) synthesized using numerous types of coating materials may exhibit different toxicity effects. The study evaluated coating material dependent toxicity by selecting 3 types of AgNP synthesis methods with different coating materials (citrate, polyvinyl pyrrolidone, and branched polyethyleneimine, coated AgNPs as citrate-AgNPs, PVP-AgNPs, and BPEI-AgNPs respectively). Two acute aquatic toxicity tests were performed; 48hr D. magna and MetPLATE E. coli toxicity tests. Significantly different toxicity effects were observed in D. magna test exhibiting lethal median concentrations (LC50) for citrate-AgNPs, PVP-AgNPs, and BPEI AgNPs respectively as, 2.7, 11.2, and 0.57μg/L. Median inhibitory concentrations (EC50) for MetPLATE tests were 1.27, 1.73, and 0.31mg/L respectively with significant different toxicity effects. Silver ion fractions were detected in the range of 2.4-19.2% in tested NP suspensions. Study suggests the toxicity effects are due to the cumulative action of ionic and nanoparticle fractions in the suspensions.
Thesis - unrestricted
Silva, Thilini Upekshika, "An Evaluation of Coating Material Dependent Toxicity of Silver Nanoparticles" (2011). Electronic Theses and Dissertations. Paper 1229. https://dc.etsu.edu/etd/1229
Copyright by the authors.