Project Title

The Effects of a High Fat/High Sugar Diet on the Myometrium

Authors' Affiliations

Cori Gilmer, Department of Health Sciences, College of Public Health, East Tennessee State University, Johnson City, TN. Dr. Allan Forsman Ph.D., Department of Health Sciences, College of Public Health, East Tennessee State University, Johnson City, TN.

Faculty Sponsor’s Department

Health Sciences

Type

Oral Non-Competitive

Classification of First Author

Undergraduate Student

Project's Category

Biological Sciences, Histology

Abstract Text

This study comprises the ramifications of a diet high in fat and sugar contents that manifest in the uterus. What a clinical setting deems excessive is unfortunately a societal norm in terms of diet. For this reason, it is of a critical nature to investigate the consequences of diets high in sugar and fat contents for the sake of women’s health. Our hypothesis is that consumption of excessive amounts of fat and sugar will have detrimental effects on the muscle layers of the uterus, the myometrium. Since much of the research concerning uterine tissue behavior involves aspects such as pregnancy and fertility assays, this study does not include such facets. The uterine horns of nine high sugar/high fat diet fed mice were collected and transversely sectioned in order to measure the thickness of each uterine layer. At the time of this submission measurements were still being taken and statistical analyses has not yet been completed.

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The Effects of a High Fat/High Sugar Diet on the Myometrium

This study comprises the ramifications of a diet high in fat and sugar contents that manifest in the uterus. What a clinical setting deems excessive is unfortunately a societal norm in terms of diet. For this reason, it is of a critical nature to investigate the consequences of diets high in sugar and fat contents for the sake of women’s health. Our hypothesis is that consumption of excessive amounts of fat and sugar will have detrimental effects on the muscle layers of the uterus, the myometrium. Since much of the research concerning uterine tissue behavior involves aspects such as pregnancy and fertility assays, this study does not include such facets. The uterine horns of nine high sugar/high fat diet fed mice were collected and transversely sectioned in order to measure the thickness of each uterine layer. At the time of this submission measurements were still being taken and statistical analyses has not yet been completed.