Degree Name

MS (Master of Science)

Program

Chemistry

Date of Award

8-2014

Committee Chair or Co-Chairs

Dr. Jeffrey Wardeska

Committee Members

Dr. Scott Kirkby, Dr. Cassandra T. Eagle

Abstract

Vanadium haloperoxidases (VHPOs) are enzymes that catalyse the oxidation of halide ions to hypohalous acids by hydrogen peroxide. There are many unanswered questions on the mechanism by which the oxidation reaction occurs. In this work, is reported the synthesis of [VO(O2)H2EDTA], studies of the effect of acid concentration on the decomposition of [VO(O2)HEDTA]-2, and mechanistic studies of the rate law. The decomposition reaction was found to be first order with respect to acid concentration and also [VO(O2)HEDTA]-2 concentration. The reaction of [VOHEDTA]-1 and hydrogen peroxide progressed via a free radical path way. In addition, the vanadium(V) complex [VO(O2)H2EDTA] was synthesized and characterised by FT-IR, UV-VIS and GC-MS. The catalytic properties of [VO(O2)H2EDTA] were investigated for an oxibromination reaction. It was found that the catalysed, and the control reaction showed no major differences except for the fact that the reaction with the catalyst gave a dibrominated product without a carbonyl group.

Document Type

Thesis - Open Access

Copyright

Copyright by the authors.

Included in

Chemistry Commons

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